GC-MS PROFILE, SYNTHESIS AND SPECTRAL CHARACTERIZATION OF FLAVONOID-METAL (CADMIUM, COBALT, COPPER, NICKEL) COMPLEXES OF JATROPHA CURCUS LEAVES

EDEWOR THERESA IBIBIA; BANKOLE T. A.; OGUNJIMI D. V.; MMUO A. I.; AMUDA M. O.

doi:10.22159/ijcr.2023v7i2.217

Authors

EDEWOR THERESA IBIBIA Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria https://orcid.org/0000-0002-1362-3763
BANKOLE T. A. Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
OGUNJIMI D. V. Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
MMUO A. I. Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
AMUDA M. O. Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria

DOI:

https://doi.org/10.22159/ijcr.2023v7i2.217

Keywords:

GC-MS, Synthesis, FTIR, UV/VIS, Flavonoids, Metals, Complexes, Jatropha curcus, Leaves

Abstract

Objective: The main aim of this research is to determine the optimum conditions required for the synthesis of metal-flavonoid complexes from leaves of Jatropha curcus.

Methods: Soxhlet extractor was used for the extraction. Phytochemical screening was carried out using the method described by Harborne. The phytochemical profile of the extract was determined using GC-MS. The flavonoid-metal complexes were synthesized using different transition metal salts and the methanolic plant leaves extract. The synthesis was carried out by varying the pH, metal ion and extract concentrations. The solubility of the flavonoid-metal complexes in different solvents was determined. The synthesized complexes were subjected to UV-visible and FTIR analysis.

Results: Methanol extract gave a yield of 4. 88%. Phytochemical screening revealed the presence of Flavonoids, steroids and alkaloids. The GC-MS analysis showed the presence of 14 compounds. Maximum dry weights of complexes formed between 600-700 mg were obtained at a concentration of 1000 ppm crude extract and for the metal ion concentrations, the optimum concentration observed for Cd²⁺and Cu²⁺complexes was 120 ppm while that of Ni²⁺and Co²⁺complexes was 140 ppm. Most suitable pH for copper-flavonoid was 8, for cobalt-and cadmium-flavonoid complexes was 9 and pH of 10 for nickel-flavonoid complexes. The FTIR results showed the formation of the complex due to the shift observed in the band assigned to C=O The UV/visible spectrum showed absorbance in the wavelength range of 250-480 nm.

Conclusion: Flavonoid-metal complexes were synthesized and their optimum conditions determine.

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