International Journal of Chemistry Research <p>International Journal of Chemistry Research (IJCR) ISSN:&nbsp;0976-5689 is a peer-reviewed, open access journal, published by Academic Sciences. It publishes Research Articles, Short communications and Review Articles in all areas of chemistry.</p> <p>Authors can submit complete unpublished and original works, which are not under review in any other journals. The scopes of the journal include, applied chemistry, inorganic chemistry, analytical chemistry, organic chemistry, physical chemistry, structural chemistry, polymer chemistry, nuclear chemistry, chemical engineering, environmental chemistry, medicinal chemistry and pharmaceutical chemistry.</p> Innovare Academic Sciences Pvt. Ltd. en-US International Journal of Chemistry Research 0976-5689 SYNTHESIS, CHARACTERIZATION AND THEORETICAL TREATMENT OF SANDWICH SCHIFF BASES COMPLEXES DERIVED FROM SALICYLALDEHYDE WITH SOME TRANSITION METALS AND STUDY OF ITS BIOLOGICAL ACTIVITY <p>Cobalt (II),Nickel (II) and Copper (II) complexes of Schiff Bases derived from Salicylaldehyde and 3,3'-diamino-diphenyl methane (L1), 3,3'-diaminodiphenyl ether (L2), 3,3'-diamino-diphenyl Sulphone (L3), were prepared and characterized by different analytical and spectral methods : elemental analysis, IR, UV-VIS, atomic absorption, Molar conductivity measurements, molar ratio studies and melting points. The Schiff bases behave as neutral tetra dentate ligands. The chloro – complexes ligands (L1, L2 and L3) with (2:2) Molar ratio showed a Sandwich structural. All complexes display an octahedral geometry around the metal center. Conductance data of the complexes suggested them to be non-electrolytes. A theoretical treatment of the formation of complexes in the gas phase was studied, this was done using the HYPERCHEM-6 program for the Molecular mechanics and Semi-empirical calculations. The free ligand and its complexes have been tested for their antibacterial activities against Two type of human pathogenic bacteria:(Staphylococcus aureus),(Escherichia coli ). the first group are Gram positive while the second group are Gram negative (by using agar well diffusion method). Finally,it was found that compounds show different activity of inhibition on growth of the bacteria.</p> OMAR HAMAD SHEHAB AL- OBAIDI Copyright (c) 2012-01-01 2012-01-01 1 5 EFFECT OF DIELECTRIC CONSTANT ON THE SOLVATION OF SODIUM CITRATE <p>The paper reports on the solvation of Sodium citrate in water, water + CH3 0 λ m CN and water + DMSO mixtures (v/v) under varying dielectric constant at different temperature. The specific conductance data obtained was analyzed by Kraus-Bray and Shedlovsky conductivity models. Limiting molar conductance ( ), dissociation constant/ association constant (KC/Ka 0 λ m ) were evaluated for all the solvent compositions. The limiting molar conductance, decreases with the increase in amount of co-solvent in water, due to increased solvent-solvent interaction and decrease in dielectric constant. Due to high viscosity and molecular size of DMSO in water, lower conductance was observed in water + DMSO media. The Ka values increases with the increase in amount co-solvent in water at all the temperatures studied. Energy of activation of the rate process and related thermodynamic parameters such as ΔHa, ΔGa and ΔSa have been evaluated. ΔGa is found to be negative indicating spontaneity of the process. Walden product (λ0mη0) and corrected Stoke’s radius (r ) have also been evaluated. Fuoss- Accascina equation was used to identify the ion-pairs and ion-triplets in the system. But the slopes of the plot were found to be less than -0.5, indicating the absence of ion-pairs or ion-triplets. Born relation of solvation was verified. These data have been used to study the nature of ion-solvent interaction and solvent-solvent interactions existing in the system</p> J ISHWARA BHAT M N MANJUNATHA Copyright (c) 2012-01-01 2012-01-01 6 14 MICROWAVE ASSISTED SOLID PHASE SYNTHESIS OF 6-METHYL-5-(SUBSTITUTED BENZOYL)-4-(SUBSTITUTED PHENYL)-3,4-DIHYDRO-1-H-PYRIMID-2-ONE/THIONE <p>Some novel substituted 3,4-dihydropyrimid-2(1H)one / thione derivatives (IVa-p) have been synthesized by condensation of corresponding chromones (i), substituted aldehydes (ii), and substituted amides (iii) in presence of catalytic amount of acetic acid under solid phase condition and microwave irradiation. The structures of the synthesized compounds have been confirmed on the basis of IR, H1 NMR, UV and Elemental analysis. The purity of compounds has been checked by HPLC technique and new protocol has been set up for newly synthesized compounds.</p> ASHISH S. SONAR PRABHA R. SOLANKI SHEETAL G. DANDALE Copyright (c) 2012-01-01 2012-01-01 15 17 A KINETIC STUDY ON THE FREE RADICAL POLYMERIZATION OF METHYL METHACRYLATEBY 1,1,4,4-TETRAMETHYL-1,4DIBENZYLETHYLENEDIAMMONIUM CHLORIDE (TMDBEDAC) AS DI-SITE PHASE TRANSFER CATALYST <p>Free radical polymerization of alkyl monomers using water soluble initiator was impractical due to phase separation, it can be overcome by<br>introduction of phase transfer catalyst (PTC). Polymerization using this technique results in polymers of high molecular weight and good<br>mechanical properties. The catalytic activity seems to increase by the aromatic substitution in the alkyl chain of PTC. In the present study kinetics of<br>polymerization of methyl methacrylate in ethyl acetate/water biphasic media using potassium peroxomonosulfate (PMS) as water soluble initiator<br>and aromatic substituted PTC was investigated. The order of the reaction was found to be unity with respect to monomer concentration and 0.5-1.0<br>for PMS and catalyst concentration. The poly methyl methacrylate formed shows high molecular weight measured from the viscosity. The product<br>formed was endorsed by IR, thermal analysis and the crystallinity was studied from X-ray diffraction.</p> M. J UMAPATHY T.G SUNITHA K.S YOGANAND G UMAMAHESWARI Copyright (c) 2012-01-01 2012-01-01 18 24 SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SUBSTITUTED p-AMINO AZOBENZENE WITH THYMOL MOIETY- A GREEN PROTOCOL <p>As a part of systematic investigation of synthesis and antimicrobial activity of p-amino azobenzene with thymol moiety from different substituted<br>aromatic amines has been achieved by simple diazotization and coupling method. The synthesized compounds have been screened in vitro for their<br>antimicrobial activity against B. subtilis, S. aureus and E.coli. Some of the compounds displayed pronounced biological activity. The resulting<br>products were characterized by IR, 1H NMR and Mass spectroscopic method.</p> MRS. PRAVINA B. PISTE DIPALI P . INDALKAR DNYANDEV N. ZAMBARE PANKAJ S. MUNDADA Copyright (c) 2012-01-01 2012-01-01 25 29 REMEDIATION OF CHLORPYRIFOS CONTAMINATED SOILS BY LABORATORY SYNTHESIZED ZERO-VALENT NANO IRON (ZVNI) PARTICLES: EFFECT OF pH AND ALUMINIUM SALTS <p>Degradation of the insecticide chlorpyrifos in contaminated soils was investigated using laboratory synthesized zero-valent nano iron (ZVNI)<br>particles. The synthesized ZVNI particles were determined as nano scale by scanning electron microscopic (SEM) and transmission electron<br>microscopic (TEM) analysis. The zero valent state (Fe0) of iron was confirmed by EDAX analysis and the morphology of the ZVNI particles was<br>studied by XRD. Batch experiments were conducted by treating the chlorpyrifos contaminated soil with ZVNI, our results indicate that 90% of<br>chlorpyrifos was degraded after 10 days of incubation. Only 32% degradation was observed with micro zero valent iron(mZVI) and no considerable<br>degradation was attained without ZVNI. The degradation of chlorpyrifos has followed the first-order kinetics with a rate constant and a half-life of<br>0.245 day-1 and 2.82 days respectively. Degradation was monitored at two different pH values i.e. pH 10 and pH 4. Chlorpyrifos degradation rate<br>constant was increased as the pH decreases from 10 to 4. The corresponding rate constant and half-lives were 0.43day-1 and 1.57days for pH 4,<br>0.18day-1 and 3.65days for pH 10. In addition, an attempt was made by augmenting Al2(SO4)3 with ZVNI and it was found that the degradation rate<br>of chlorpyrifos was greatly enhanced and the rate constant was rapidly increased from 0.245day-1 to 0.60day-1. Hydrolysis and stepwise dechlorination pathway of chlorpyrifos with ZVNI was the dominant reaction.</p> Dr. G. MADHAVI A. VIJAYA BHASKAR REDDY V. MADHAVI Copyright (c) 2012-01-01 2012-01-01 30 35 ADSORPTION OF REACTIVE DYE BY A NOVEL ACTIVATED CARBON PREPARED FROM THEVETIA PERUVIANA <p>This investigation was to evaluate the adsorption capability of activated carbon prepared from Thevetia Peruviana wood for removal of reactive<br>textile dye (RO4) from aqueous solution. Batch adsorption experiments were performed as a function of initial dye concentration, contact time,<br>temperature and pH. The amount of dye adsorbed increased while increasing the initial concentration and temperature of the solution. The<br>experimental data fitted well to Pseudo second order kinetic model with Intra particle diffusion as the rate determining step. Adsorption data fitted<br>with Langmuir model. The negative value of Gibb’s free energy (∆G°) indicated that the adsorption was spontaneous in nature. The results showed<br>that the activated carbon of Thevetia Peruviana was suitable for the removal of the reactive dyes from the aqueous solutions. The positive value of<br>enthalpy (∆H° ) indicated that the adsorption of the selected dyes were endothermic.</p> J. RAFFIEA BASERI P. N. PALANISAMY P. SIVAKUMAR Copyright (c) 2012-01-01 2012-01-01 36 41 SYNTHESIS OF POLY (L-LACTIC ACID) BY EHYDROPOLYCONDENSATION, DETERMINATION OF SEQUENCE BY 13C NMR METHOD <p>The proposed work was undertaken to synthesize high molecular weight PLA by direct polycondensation to find its better applicability in fiber<br>application, packaging material and commodity. However, it was reported that it was very difficult to obtain high molecular weight PLA by direct<br>polycondensation because of equilibrium between free acids, water and polyesters causing difficulty in removing water as a by-product. The effect<br>of various solvents (polar and non polar) and reaction temperatures were also investigated. In this contribution, the influence of process variables<br>on the molecular weight of PLA synthesized by direct polycondensation will be highlighted. We report the use of high-resolution 13C-NMR (125<br>MHz) spectroscopy to identify the sterosequence distribution and determine stereo specific preference for L-lactic acid addition during tin chloride<br>dihydrate (SnCl2.2H2O) catalyzed polymerization, and effect of various specific polymerization conditions such as temperature, duration of reaction<br>and the nature of solvents.</p> ASUTOSH KUMAR PANDEY Copyright (c) 2012-01-01 2012-01-01 42 51 SYNTHESIS, CHARACTERIZATION AND DE-TERTBUTYLATION OF 4-ARYLIMINO-3-TERTBUTYL-1, 3, 4, 5-TETRAHYDRO-2H-1,3,5-BENZOTRIAZEPINE-2-THIONES <p>Some new 4-aryl imino -3-tert-butyl-l,3,4,5-tetrahydro-2H-1,3,5-benzotriazepine-2 thione (Va-e) were synthesized via 2-aryl imino –N-4-tertbutylimino-4,5-dihydro-3,1,5- benzothiadiazepine (IVa-e) by the condensation of 1-(2-aminophenyl)-3-phenyl thioureas (IIa-e) with tert-butyl<br>imino isocyanodichloride. The 1-(2-aminophenyl)-3-phenyl thioureas (IIa-e) were obtained by the treatment of o-phenylene diamine and aryl<br>isothiocyanates. The synthesized compounds 4-aryl imino -3-tert-butyl-l,3,4,5-tetrahydro-2H-1,3,5-benzotriazepine-2-thione (Va-e) were<br>successfully de-tertbutylated into respective 4-arylimino-1,3,4,5-tetrahydro-2H-1,3,5-benzotriazepine-2-thiones (VIa-e).</p> NAZIA A RASHIDI B. N. BERAD Copyright (c) 2012-01-01 2012-01-01 52 55