INVESTIGATION OF CANCER CELLS USING THIN LAYERS OF CADMIUM OXIDE (CdO)–DNA/RNA SANDWICHED COMPLEX COMPOSITE PLASMONIC NANOSTRUCTURE UNDER SYNCHROTRON RADIATION

ALIREZA HEIDARI

doi:10.22159/ijcr.2022v6i1.180

Authors

ALIREZA HEIDARI Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604, USA, BioSpectroscopy Core Research Laboratory, California South University, 14731 Comet St. Irvine, CA 92604, USA, Cancer Research Institute (CRI), California South University, 14731 Comet St. Irvine, CA 92604, USA, American International Standards Institute, Irvine, CA 3800, USA

DOI:

https://doi.org/10.22159/ijcr.2022v6i1.180

Keywords:

Elimination, Cancer cells, Thin layers, Cadmium oxide (CdO), Plasmonic nanostructure, Synchrotron radiation, Triptycene barrelene anthracene (TBA), DNA/RNA, Polyether ether ketone (PEEK), Sandwiched complex, Composite, Anti–cancer-protective membrane

Abstract

Triptycene Barrelene Anthracene (TBA) is a polycyclic aromatic hydrocarbon consisting of three benzene rings. The name TBA is a composite of phenyl and TBA. In its pure form, it is found in cigarette smoke and is a known irritant, photosensitizing skin and industrial carcinogenic wastewater. Cadmium Oxide (CdO) is an inorganic compound with the formula CdO. It is one of the main precursors to other cadmium compounds. It crystallizes in a cubic rocksalt lattice-like sodium chloride, with octahedral cation and anion centers. It occurs naturally as the rare mineral monteponite. CdO can be found as a colorless amorphous powder or as brown or red crystals. CdO is an n-type semiconductor with a bandgap of 2.18 eV (2.31 eV) at room temperature (298 K). DNA/RNA, CdO and DNA/RNA–CdO sandwiched complex was characterized by Attenuated Total Reflection–Fourier Transform–Infrared (ATR–FTIR) spectroscopy, Raman spectroscopy, X–Ray Diffraction (XRD) technique and Energy–Dispersive X–Ray (EDAX) spectroscopy. The modified anti–cancer-protective membrane was characterized by Scanning Electron Microscope (SEM), EDAX analysis, 3D–Atomic–Force Microscopy (3D–AFM), Transmission Electron Microscopy (TEM) and contact angle analyses and methods. The current study is aimed to use Polysorbate 80 as a surfactant for investigating the effectiveness of permeate TBA on the Polyether Ether Ketone (PEEK) anti–cancer-protective membrane and the effect of loading DNA/RNA–CdO sandwiched complex on hydrophilicity and anti-cancer properties. The results showed decreasing surface pore size from 227 to 176 and increasing porosity from 101 to 111 with loading DNA/RNA–CdO sandwiched complex, and the permeate of anti–cancer-protective membrane increased from 80 to 220 (L/m2. hr. bar) with loading DNA/RNA–CdO sandwiched complex.

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